CD34 Mouse Monoclonal Antibody [Clone ID: OTI8F11]

Specifications

Product Data
Clone Name	OTI8F11
Applications	IHC, WB
Recommend Dilution	WB 1:500, IHC 1:150
Reactivity	Human
Host	Mouse
Clonality	Monoclonal
Immunogen	Human recombinant protein fragment corresponding to amino acids 312-385 of human CD34(NP_001020280) produced in E.coli.
Isotype	IgG2a
Formulation	PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Concentration	1 mg/ml
Purification	Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	40.5 kDa
Gene Name	CD34 molecule
Database Link	NP_001020280 Entrez Gene 947 Human UniProt ID P28906
Background	Possible adhesion molecule with a role in early hematopoiesis by mediating the attachment of stem cells to the bone marrow extracellular matrix or directly to stromal cells. Could act as a scaffold for the attachment of lineage specific glycans, allowing stem cells to bind to lectins expressed by stromal cells or other marrow components. Presents carbohydrate ligands to selectins. [UniProtKB/Swiss-Prot Function]
Reference Data
Protein Families	Adult stem cells, Cancer stem cells, Druggable Genome, Embryonic stem cells, ES Cell Differentiation/IPS, Transmembrane
Protein Pathways	Cell adhesion molecules (CAMs), Hematopoietic cell lineage

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