CNOT2 Mouse Monoclonal Antibody (Biotin conjugated) [Clone ID: OTI5A12]

Specifications

Product Data
Clone Name	OTI5A12
Applications	IHC, WB
Recommend Dilution	WB 1:2000, IHC 1:150
Reactivity	Human, Mouse, Rat
Host	Mouse
Clonality	Monoclonal
Immunogen	Full length human recombinant protein of human CNOT2(NP_055330) produced in E.coli.
Isotype	IgG2b
Formulation	PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Concentration	0.5 mg/ml
Purification	Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation	Biotin
Storage Condition	Store at -20°C as received.
Predicted Protein Size	59.6 kDa
Gene Name	CCR4-NOT transcription complex subunit 2
Database Link	NP_055330 Entrez Gene 72068 MouseEntrez Gene 299805 RatEntrez Gene 4848 Human UniProt ID Q9NZN8
Background	This gene encodes a subunit of the multi-component CCR4-NOT complex. The CCR4-NOT complex regulates mRNA synthesis and degradation and is also thought to be involved in mRNA splicing, transport and localization. The encoded protein interacts with histone deacetylases and functions as a repressor of polymerase II transcription. Alternatively spliced transcript variants have been observed for this gene. [provided by RefSeq, Dec 2010]
Synonyms	CDC36; HSPC131; NOT2; NOT2H
Reference Data
Protein Families	Transcription Factors
Protein Pathways	RNA degradation

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