EXOSC1 Mouse Monoclonal Antibody [Clone ID: OTI4B7]

Specifications

Product Data
Clone Name	OTI4B7
Applications	IHC, WB
Recommend Dilution	WB 1:2000, IHC 1:150
Reactivity	Human, Mouse, Rat
Host	Mouse
Clonality	Monoclonal
Immunogen	Full length human recombinant protein of human EXOSC1 (NP_057130) produced in E.coli.
Isotype	IgG1
Formulation	PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Concentration	1 mg/ml
Purification	Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	21.3 kDa
Gene Name	exosome component 1
Database Link	NP_057130 Entrez Gene 51013 Human UniProt ID Q9Y3B2
Background	This gene encodes a core component of the exosome. The mammalian exosome is required for rapid degradation of AU rich element-containing RNAs but not for poly(A) shortening. The association of this protein with the exosome is mediated by protein-protein interactions with ribosomal RNA-processing protein 42 and ribosomal RNA-processing protein 46. [provided by RefSeq, Jul 2008]
Synonyms	CGI-108; CSL4; Csl4p; hCsl4p; p13; SKI4; Ski4p
Reference Data
Protein Pathways	RNA degradation

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