URP2 (FERMT3) Mouse Monoclonal Antibody [Clone ID: OTI2H10]

Specifications

Product Data
Clone Name	OTI2H10
Applications	IHC, WB
Recommend Dilution	WB 1:500, IHC 1:150
Reactivity	Human, Mouse, Rat
Host	Mouse
Clonality	Monoclonal
Immunogen	Human recombinant protein fragment corresponding to amino acids 259-528 of human FERMT3(NP_113659) produced in E.coli.
Isotype	IgG1
Formulation	PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Concentration	1 mg/ml
Purification	Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	75.2 kDa
Gene Name	fermitin family member 3
Database Link	NP_113659 Entrez Gene 108101 MouseEntrez Gene 309186 RatEntrez Gene 83706 Human UniProt ID Q86UX7
Background	Kindlins are a small family of proteins that mediate protein-protein interactions involved in integrin activation and thereby have a role in cell adhesion, migration, differentiation, and proliferation. The protein encoded by this gene has a key role in the regulation of hemostasis and thrombosis. This protein may also help maintain the membrane skeleton of erythrocytes. Mutations in this gene cause the autosomal recessive leukocyte adhesion deficiency syndrome-III (LAD-III). Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Jan 2010]
Synonyms	KIND3; MIG-2; MIG2B; UNC112C; URP2; URP2SF
Reference Data

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