NR0B1 Mouse Monoclonal Antibody [Clone ID: OTI5F5]

Specifications

Product Data
Clone Name	OTI5F5
Applications	IHC, WB
Recommend Dilution	IHC 1:150
Reactivity	Human
Host	Mouse
Clonality	Monoclonal
Immunogen	Human recombinant protein fragment corresponding to amino acids 161-430 of human NR0B1 (NP_000466) produced in E.coli.
Isotype	IgG1
Formulation	PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Concentration	1 mg/ml
Purification	Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	51.5 kDa
Gene Name	nuclear receptor subfamily 0 group B member 1
Database Link	NP_000466 Entrez Gene 190 Human UniProt ID P51843
Background	This gene encodes a protein that contains a DNA-binding domain. The encoded protein acts as a dominant-negative regulator of transcription which is mediated by the retinoic acid receptor. This protein also functions as an anti-testis gene by acting antagonistically to Sry. Mutations in this gene result in both X-linked congenital adrenal hypoplasia and hypogonadotropic hypogonadism. [provided by RefSeq, Jul 2008]
Synonyms	AHC; AHCH; AHX; DAX-1; DAX1; DSS; GTD; HHG; NROB1; SRXY2
Reference Data
Protein Families	Druggable Genome, Nuclear Hormone Receptor, Transcription Factors

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