RSPO1 Mouse Monoclonal Antibody [Clone ID: OTI1C3]

Specifications

Product Data
Clone Name	OTI1C3
Applications	IHC, WB
Recommend Dilution	WB 1:2000, IHC 1:150
Reactivity	Human, Mouse, Rat
Host	Mouse
Clonality	Monoclonal
Immunogen	Human recombinant protein fragment corresponding to amino acids 21-263 of human RSPO1 (NP_001033722) produced in E.coli.
Isotype	IgG1
Formulation	PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Concentration	1 mg/ml
Purification	Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	28.8 kDa
Gene Name	R-spondin 1
Database Link	NP_001033722 Entrez Gene 192199 MouseEntrez Gene 313589 RatEntrez Gene 284654 Human UniProt ID Q2MKA7
Background	This gene is a member of the R-spondin family and encodes a secreted activator protein with two cystein-rich, furin-like domains and one thrombospondin type 1 domain. In mice, the protein induces the rapid onset of crypt cell proliferation and increases intestinal epithelial healing, providing a protective effect against chemotherapy-induced adverse effects. [provided by RefSeq, Jul 2008]
Synonyms	CRISTIN3; RSPO
Reference Data
Protein Families	Secreted Protein

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