PAFAH1B3 Mouse Monoclonal Antibody (Biotin conjugated) [Clone ID: OTI4A9]

Specifications

Product Data
Clone Name	OTI4A9
Applications	IHC, WB
Recommend Dilution	WB 1:2000, IHC 1:150
Reactivity	Human, Mouse, Rat
Host	Mouse
Clonality	Monoclonal
Immunogen	Full length human recombinant protein of human PAFAH1B3 (NP_001139411) produced in E.coli.
Isotype	IgG1
Formulation	PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Concentration	0.5 mg/ml
Purification	Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation	Biotin
Storage Condition	Store at -20°C as received.
Predicted Protein Size	25.6 kDa
Gene Name	platelet activating factor acetylhydrolase 1b catalytic subunit 3
Database Link	NP_001139411 Entrez Gene 5050 Human UniProt ID Q15102
Background	This gene encodes an acetylhydrolase that catalyzes the removal of an acetyl group from the glycerol backbone of platelet-activating factor. The encoded enzyme is a subunit of the platelet-activating factor acetylhydrolase isoform 1B complex, which consists of the catalytic beta and gamma subunits and the regulatory alpha subunit. This complex functions in brain development. A translocation between this gene on chromosome 19 and the CDC-like kinase 2 gene on chromosome 1 has been observed, and was associated with mental retardation, ataxia, and atrophy of the brain. Alternatively spliced transcript variants have been described. [provided by RefSeq, Mar 2009]
Synonyms	PAFAHG
Reference Data
Protein Families	Druggable Genome
Protein Pathways	Ether lipid metabolism, Metabolic pathways

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