Smad Interacting Protein 1 (ZEB2) Mouse Monoclonal Antibody (Biotin conjugated) [Clone ID: OTI1E12]

Specifications

Product Data
Clone Name	OTI1E12
Applications	IHC, WB
Recommend Dilution	WB 1:2000, IHC 1:150
Reactivity	Human, Mouse, Rat
Host	Mouse
Clonality	Monoclonal
Immunogen	Human recombinant protein fragment corresponding to amino acids 1-350 of human ZEB2 (NP_055610) produced in E.coli.
Isotype	IgG1
Formulation	PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Concentration	0.5 mg/ml
Purification	Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation	Biotin
Storage Condition	Store at -20°C as received.
Gene Name	zinc finger E-box binding homeobox 2
Database Link	NP_055610 Entrez Gene 24136 MouseEntrez Gene 311071 RatEntrez Gene 9839 Human UniProt ID O60315
Background	The protein encoded by this gene is a member of the Zfh1 family of 2-handed zinc finger/homeodomain proteins. It is located in the nucleus and functions as a DNA-binding transcriptional repressor that interacts with activated SMADs. Mutations in this gene are associated with Hirschsprung disease/Mowat-Wilson syndrome. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jan 2010]
Synonyms	HSPC082; SIP-1; SIP1; SMADIP1; ZFHX1B
Reference Data
Protein Families	Druggable Genome, Transcription Factors

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