Kallikrein 2 (KLK2) Mouse Monoclonal Antibody [Clone ID: OTI5D6]

Specifications

Product Data
Clone Name	OTI5D6
Applications	IHC, WB
Recommend Dilution	WB 1:2000, IHC 1:150
Reactivity	Human
Host	Mouse
Clonality	Monoclonal
Immunogen	Human recombinant protein fragment corresponding to amino acids 25-261 of human KLK2 (NP_005542) produced in SF9 cell.
Isotype	IgG2b
Formulation	PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Concentration	1 mg/ml
Purification	Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	28.5 kDa
Gene Name	kallikrein related peptidase 2
Database Link	NP_005542 Entrez Gene 3817 Human UniProt ID P20151
Background	This gene encodes a member of the grandular kallikrein protein family. Kallikreins are a subgroup of serine proteases that are clustered on chromosome 19. Members of this family are involved in a diverse array of biological functions. The protein encoded by this gene is a highly active trypsin-like serine protease that selectively cleaves at arginine residues. This protein is primarily expressed in prostatic tissue and is responsible for cleaving pro-prostate-specific antigen into its enzymatically active form. This gene is highly expressed in prostate tumor cells and may be a prognostic maker for prostate cancer risk. Alternate splicing results in both coding and non-coding transcript variants. [provided by RefSeq, Jan 2012]
Synonyms	hGK-1; hK2; KLK2A2
Reference Data
Protein Families	Druggable Genome, Protease

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