ALK Rat Monoclonal Antibody (HRP conjugated) [Clone ID: OTI1C2]

CAT#: TA801074BM

ALK rat monoclonal antibody, clone OTI1C2 (formerly 1C2), HRP conjugated

Conjugation: Unconjugated Biotin HRP



  View other "OTI1C2" antibodies (4)

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CNY 3,990.00


货期*
2周

规格
    • 100 ul

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beta Actin Mouse Monoclonal Antibody, Clone OTI1, Loading Control
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Recombinant protein of human anaplastic lymphoma receptor tyrosine kinase (ALK), 20 µg
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Transient overexpression lysate of anaplastic lymphoma receptor tyrosine kinase (ALK)
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Specifications

Product Data
Clone Name OTI1C2
Applications WB
Recommend Dilution WB 1:2000
Reactivity Human, Mouse, Rat
Host Rat
Clonality Monoclonal
Immunogen Human recombinant protein fragment corresponding to amino acids 1060-1620 of human ALK (NP_004295) produced in SF9 cell.
Formulation PBS (pH 7.3) containing 1% BSA, 50% glycerol.
Concentration 0.5 mg/ml
Purification Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation HRP
Storage Condition Store at -20°C as received.
Predicted Protein Size 176.3 kDa
Gene Name anaplastic lymphoma receptor tyrosine kinase
Background This gene encodes a receptor tyrosine kinase, which belongs to the insulin receptor superfamily. This protein comprises an extracellular domain, an hydrophobic stretch corresponding to a single pass transmembrane region, and an intracellular kinase domain. It plays an important role in the development of the brain and exerts its effects on specific neurons in the nervous system. This gene has been found to be rearranged, mutated, or amplified in a series of tumours including anaplastic large cell lymphomas, neuroblastoma, and non-small cell lung cancer. The chromosomal rearrangements are the most common genetic alterations in this gene, which result in creation of multiple fusion genes in tumourigenesis, including ALK (chromosome 2)/EML4 (chromosome 2), ALK/RANBP2 (chromosome 2), ALK/ATIC (chromosome 2), ALK/TFG (chromosome 3), ALK/NPM1 (chromosome 5), ALK/SQSTM1 (chromosome 5), ALK/KIF5B (chromosome 10), ALK/CLTC (chromosome 17), ALK/TPM4 (chromosome 19), and ALK/MSN (chromosome X). [provided by RefSeq, Jan 2011]
Synonyms CD246; NBLST3
Reference Data
Protein Families Druggable Genome, Protein Kinase
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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