SLUG (SNAI2) Mouse Monoclonal Antibody [Clone ID: OTI2B11]

Specifications

Product Data
Clone Name	OTI2B11
Applications	FC, IF, IHC, WB
Recommend Dilution	WB 1:2000, IHC 1:150, IF 1:100, FLOW 1:100
Reactivity	Human, Mouse, Rat
Host	Mouse
Clonality	Monoclonal
Immunogen	Full length human recombinant protein of human SNAI2 (NP_003059) produced in E.coli.
Isotype	IgG1
Formulation	PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Concentration	1 mg/ml
Purification	Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	29.8 kDa
Gene Name	snail family transcriptional repressor 2
Database Link	NP_003059 Entrez Gene 20583 MouseEntrez Gene 25554 RatEntrez Gene 6591 Human UniProt ID O43623
Background	This gene encodes a member of the Snail family of C2H2-type zinc finger transcription factors. The encoded protein acts as a transcriptional repressor that binds to E-box motifs and is also likely to repress E-cadherin transcription in breast carcinoma. This protein is involved in epithelial-mesenchymal transitions and has antiapoptotic activity. Mutations in this gene may be associated with sporatic cases of neural tube defects. [provided by RefSeq]
Synonyms	SLUG; SLUGH; SLUGH1; SNAIL2; WS2D
Reference Data
Protein Families	Druggable Genome, Transcription Factors
Protein Pathways	Adherens junction

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