SENP1 Mouse Monoclonal Antibody (Biotin conjugated) [Clone ID: OTI1D7]

Specifications

Product Data
Clone Name	OTI1D7
Applications	FC, WB
Recommend Dilution	WB 1:1000, FLOW 1:100
Reactivity	Human, Mouse, Rat
Host	Mouse
Clonality	Monoclonal
Immunogen	Human recombinant protein fragment corresponding to amino acids 221-460 of human SENP1 (NP_055369) produced in E.coli.
Isotype	IgG1
Formulation	PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Concentration	0.5 mg/ml
Purification	Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation	Biotin
Storage Condition	Store at -20°C as received.
Predicted Protein Size	73.2 kDa
Gene Name	SUMO1/sentrin specific peptidase 1
Database Link	NP_055369 Entrez Gene 223870 MouseEntrez Gene 29843 Human UniProt ID Q9P0U3
Background	The covalent modification of proteins by the small ubiquitin (UBB; MIM 191339)-like protein SUMO (see SUMO1, MIM 601912) is implicated in the regulation of nucleocytoplasmic transport, genomic stability, gene transcription, and other processes. Sumoylation is catalyzed on target lysine residues by a multienzyme process and is reversed by desumoylating enzymes such as SENP1 (Yamaguchi et al., 2005 [PubMed 15923632]). [supplied by OMIM]
Synonyms	SuPr-2
Reference Data
Protein Families	Druggable Genome, Protease

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