SOX2 Rabbit Monoclonal Antibody [Clone ID: OTIR-2D11]

Specifications

Product Data
Clone Name	OTIR-2D11
Applications	WB
Recommend Dilution	WB: 1:500-1:2000
Reactivity	Human, Mouse, Rat
Host	Rabbit
Clonality	Monoclonal
Immunogen	Synthetic peptide (the amino acid sequence is considered to be commercially sensitive) within Human SOX2 ( NP_003097). The exact sequence is proprietary.
Isotype	IgG
Formulation	PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Purification	Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	34.1 kDa
Gene Name	SRY-box transcription factor 2
Database Link	NP_003097 Entrez Gene 20674 MouseEntrez Gene 499593 RatEntrez Gene 6657 Human UniProt ID P48431
Background	This intronless gene encodes a member of the SRY-related HMG-box (SOX) family of transcription factors involved in the regulation of embryonic development and in the determination of cell fate. The product of this gene is required for stem-cell maintenance in the central nervous system, and also regulates gene expression in the stomach. Mutations in this gene have been associated with optic nerve hypoplasia and with syndromic microphthalmia, a severe form of structural eye malformation. This gene lies within an intron of another gene called SOX2 overlapping transcript (SOX2OT). [provided by RefSeq, Jul 2008]
Synonyms	ANOP3; MCOPS3
Reference Data
Protein Families	Adult stem cells, Cancer stem cells, Embryonic stem cells, ES Cell Differentiation/IPS, Induced pluripotent stem cells, Transcription Factors

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