IL1 beta (IL1B) Mouse Monoclonal Antibody (Biotin conjugated) [Clone ID: OTI1A7]

CAT#: TA506440AM

IL1B mouse monoclonal antibody,clone 1A7, Biotinylated

Conjugation: Unconjugated Biotin HRP



  View other "OTI1A7" antibodies (4)

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CNY 3,990.00


货期*
2周

规格
    • 100 ul

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Specifications

Product Data
Clone Name OTI1A7
Applications WB
Recommend Dilution WB 1:4000
Reactivity Human
Host Mouse
Clonality Monoclonal
Immunogen Full length human recombinant protein of human IL1B(NP_000567) produced in HEK293T cell.
Formulation PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Concentration 0.5 mg/ml
Purification Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation Biotin
Storage Condition Store at -20°C as received.
Predicted Protein Size 30.6 kDa
Gene Name interleukin 1 beta
Background The protein encoded by this gene is a member of the interleukin 1 cytokine family. This cytokine is produced by activated macrophages as a proprotein, which is proteolytically processed to its active form by caspase 1 (CASP1/ICE). This cytokine is an important mediator of the inflammatory response, and is involved in a variety of cellular activities, including cell proliferation, differentiation, and apoptosis. The induction of cyclooxygenase-2 (PTGS2/COX2) by this cytokine in the central nervous system (CNS) is found to contribute to inflammatory pain hypersensitivity. This gene and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2. [provided by RefSeq, Jul 2008]
Synonyms IL-1; IL1-BETA; IL1F2
Reference Data
Protein Families Druggable Genome, Secreted Protein
Protein Pathways Alzheimer's disease, Apoptosis, Cytokine-cytokine receptor interaction, Cytosolic DNA-sensing pathway, Graft-versus-host disease, Hematopoietic cell lineage, MAPK signaling pathway, NOD-like receptor signaling pathway, Prion diseases, Toll-like receptor signaling pathway, Type I diabetes mellitus
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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