CD19 Mouse Monoclonal Antibody (Biotin conjugated) [Clone ID: OTI3B10]

Specifications

Product Data
Clone Name	OTI3B10
Applications	FC, IF, IHC, WB
Recommend Dilution	WB 1:4000, IHC 1:150, IF 1:100
Reactivity	Human
Host	Mouse
Clonality	Monoclonal
Immunogen	Full length human recombinant protein of human CD19(NP_001761) produced in HEK293T cell.
Isotype	IgG1
Concentration	0.5 mg/ml
Purification	Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation	Biotin
Storage Condition	Store at -20°C as received.
Predicted Protein Size	60.9 kDa
Gene Name	CD19 molecule
Database Link	NP_001761 Entrez Gene 930 Human UniProt ID P15391
Background	Lymphocytes proliferate and differentiate in response to various concentrations of different antigens. The ability of the B cell to respond in a specific, yet sensitive manner to the various antigens is achieved with the use of low-affinity antigen receptors. This gene encodes a cell surface molecule which assembles with the antigen receptor of B lymphocytes in order to decrease the threshold for antigen receptor-dependent stimulation. [provided by RefSeq, Jul 2008]
Synonyms	B4; CVID3
Reference Data
Protein Families	Druggable Genome, Transmembrane
Protein Pathways	B cell receptor signaling pathway, Hematopoietic cell lineage, Primary immunodeficiency

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