ADAMTS8 Mouse Monoclonal Antibody [Clone ID: OTI2H5]

Specifications

Product Data
Clone Name	OTI2H5
Applications	IF, WB
Recommend Dilution	WB 1:1000, IF 1:100
Reactivity	Human
Host	Mouse
Clonality	Monoclonal
Immunogen	Full length human recombinant protein of human ADAMTS8(NP_008968) produced in HEK293T cell.
Isotype	IgG1
Formulation	PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Concentration	1 mg/ml
Purification	Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	96.3 kDa
Gene Name	ADAM metallopeptidase with thrombospondin type 1 motif 8
Database Link	NP_008968 Entrez Gene 11095 Human UniProt ID Q9UP79
Background	This gene encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) protein family. Members of the family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The enzyme encoded by this gene contains two C-terminal TS motifs, and disrupts angiogenesis in vivo. A number of disorders have been mapped in the vicinity of this gene, most notably lung neoplasms. [provided by RefSeq, Jul 2008]
Synonyms	ADAM-TS8; METH2
Reference Data
Protein Families	Druggable Genome, Protease, Secreted Protein

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