DOK7 Mouse Monoclonal Antibody [Clone ID: OTI1A9]

Specifications

Product Data
Clone Name	OTI1A9
Applications	FC, IF, IHC, WB
Recommend Dilution	WB 1:500~2000, IHC 1:150, IF 1:100, FLOW 1:100
Reactivity	Human, Mouse
Host	Mouse
Clonality	Monoclonal
Immunogen	Full length human recombinant protein of human DOK7(NP_775931) produced in HEK293T cell.
Isotype	IgG1
Formulation	PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Concentration	1 mg/ml
Purification	Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	52.9 kDa
Gene Name	docking protein 7
Database Link	NP_775931 Entrez Gene 231134 MouseEntrez Gene 285489 Human UniProt ID Q18PE1
Background	The protein encoded by this gene is essential for neuromuscular synaptogenesis. The protein functions in aneural activation of muscle-specific receptor kinase, which is required for postsynaptic differentiation, and in the subsequent clustering of the acetylcholine receptor in myotubes. This protein can also induce autophosphorylation of muscle-specific receptor kinase. Mutations in this gene are a cause of familial limb-girdle myasthenia autosomal recessive, which is also known as congenital myasthenic syndrome type 1B. Alternative splicing results in multiple transcript variants. [provided by RefSeq]
Synonyms	C4orf25; CMS1B; CMS10
Reference Data

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