PALS1 Mouse Monoclonal Antibody [Clone ID: OTI2D3]

Specifications

Product Data
Clone Name	OTI2D3
Applications	FC, WB
Recommend Dilution	WB 1:500~2000, FLOW 1:100
Reactivity	Human, Dog, Rat, Mouse
Host	Mouse
Clonality	Monoclonal
Immunogen	Full length human recombinant protein of human MPP5(NP_071919) produced in HEK293T cell.
Isotype	IgG2a
Formulation	PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Concentration	0.88 mg/ml
Purification	Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	77.1 kDa
Gene Name	protein associated with LIN7 1, MAGUK family member
Database Link	NP_071919 Entrez Gene 314259 RatEntrez Gene 490740 DogEntrez Gene 64398 Human UniProt ID Q8N3R9
Background	This gene encodes a member of the p55-like subfamily of the membrane-associated guanylate kinase (MAGUK) gene superfamily. The encoded protein participates in the polarization of differentiating cells, has been shown to regulate myelinating Schwann cells (PMID: 20237282), and is one of the components of the Crumbs complex in the retina. Mice which express lower levels of the orthologous protein have retinal degeneration and impaired vision (PMID: 22114289). Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2012]
Synonyms	PALS1
Reference Data
Protein Families	Druggable Genome
Protein Pathways	Tight junction

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