BCAT1 Mouse Monoclonal Antibody [Clone ID: OTI3F5]

Specifications

Product Data
Clone Name	OTI3F5
Applications	IHC, WB
Recommend Dilution	WB 1:500~2000, IHC 1:150
Reactivity	Human, Dog, Mouse
Host	Mouse
Clonality	Monoclonal
Immunogen	Full length human recombinant protein of human BCAT1(NP_005495) produced in HEK293T cell.
Isotype	IgG2a
Formulation	PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Concentration	Lot dependent
Purification	Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	42.8 kDa
Gene Name	branched chain amino acid transaminase 1
Database Link	NP_005495 Entrez Gene 12035 MouseEntrez Gene 486633 DogEntrez Gene 586 Human UniProt ID P54687
Background	This gene encodes the cytosolic form of the enzyme branched-chain amino acid transaminase. This enzyme catalyzes the reversible transamination of branched-chain alpha-keto acids to branched-chain L-amino acids essential for cell growth. Two different clinical disorders have been attributed to a defect of branched-chain amino acid transamination: hypervalinemia and hyperleucine-isoleucinemia. As there is also a gene encoding a mitochondrial form of this enzyme, mutations in either gene may contribute to these disorders. Alternatively spliced transcript variants have been described. [provided by RefSeq]
Synonyms	BCATC; BCT1; ECA39; MECA39; PNAS121; PP18
Reference Data
Protein Families	Druggable Genome
Protein Pathways	Metabolic pathways, Pantothenate and CoA biosynthesis, Valine, leucine and isoleucine biosynthesis, Valine, leucine and isoleucine degradation

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