DGKA Mouse Monoclonal Antibody [Clone ID: OTI3G7]

Specifications

Product Data
Clone Name	OTI3G7
Applications	FC, WB
Recommend Dilution	WB 1:500~2000, FLOW 1:100
Reactivity	Human, Dog, Rat
Host	Mouse
Clonality	Monoclonal
Immunogen	Full length human recombinant protein of human DGKA(NP_001336) produced in HEK293T cell.
Isotype	IgG2a
Formulation	PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Concentration	0.67 mg/ml
Purification	Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	82.5 kDa
Gene Name	diacylglycerol kinase alpha
Database Link	NP_001336 Entrez Gene 140866 RatEntrez Gene 100855691 DogEntrez Gene 1606 Human UniProt ID P23743
Background	The protein encoded by this gene belongs to the eukaryotic diacylglycerol kinase family. It acts as a modulator that competes with protein kinase C for the second messenger diacylglycerol in intracellular signaling pathways. It also plays an important role in the resynthesis of phosphatidylinositols and phosphorylating diacylglycerol to phosphatidic acid. Alternative splicing occurs at this locus and four transcript variants encoding the same protein have been identified. [provided by RefSeq]
Synonyms	DAGK; DAGK1; DGK-alpha
Reference Data
Protein Families	Druggable Genome
Protein Pathways	Glycerolipid metabolism, Glycerophospholipid metabolism, Metabolic pathways, Phosphatidylinositol signaling system

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