ARH (LDLRAP1) Mouse Monoclonal Antibody (Biotin conjugated) [Clone ID: OTI5A12]

Specifications

Product Data
Clone Name	OTI5A12
Applications	FC, IF, WB
Recommend Dilution	WB 1:2000, IF 1:100, FLOW 1:100
Reactivity	Human, Mouse, Rat
Host	Mouse
Clonality	Monoclonal
Immunogen	Full length human recombinant protein of human LDLRAP1(NP_056442) produced in HEK293T cell.
Isotype	IgG1
Formulation	PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Concentration	0.5 mg/ml
Purification	Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation	Biotin
Storage Condition	Store at -20°C as received.
Predicted Protein Size	33.7 kDa
Gene Name	low density lipoprotein receptor adaptor protein 1
Database Link	NP_056442 Entrez Gene 100017 MouseEntrez Gene 500564 RatEntrez Gene 26119 Human UniProt ID Q5SW96
Background	The protein encoded by this gene is a cytosolic protein which contains a phosphotyrosine binding (PTD) domain. The PTD domain has been found to interact with the cytoplasmic tail of the LDL receptor. Mutations in this gene lead to LDL receptor malfunction and cause the disorder autosomal recessive hypercholesterolaemia. [provided by RefSeq, Jul 2008]
Synonyms	ARH; ARH1; ARH2; FHCB1; FHCB2
Reference Data
Protein Families	Druggable Genome
Protein Pathways	Endocytosis

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