LCMT1 Mouse Monoclonal Antibody (Biotin conjugated) [Clone ID: OTI1G5]

Specifications

Product Data
Clone Name	OTI1G5
Applications	FC, IF, IHC, WB
Recommend Dilution	WB 1:2000, IHC 1:150, IF 1:100, FLOW 1:100
Reactivity	Human, Mouse, Rat
Host	Mouse
Clonality	Monoclonal
Immunogen	Full length human recombinant protein of human LCMT1(NP_057393) produced in HEK293T cell.
Isotype	IgG2b
Formulation	PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Concentration	0.5 mg/ml
Purification	Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation	Biotin
Storage Condition	Store at -20°C as received.
Predicted Protein Size	38.2 kDa
Gene Name	leucine carboxyl methyltransferase 1
Database Link	NP_057393 Entrez Gene 30949 MouseEntrez Gene 361643 RatEntrez Gene 51451 Human UniProt ID Q9UIC8
Background	LCMT1 catalyzes the methylation of the carboxyl group of the C-terminal leucine residue (leu309) of the catalytic subunit of protein phosphatase-2A (PPP2CA; MIM 176915) (De Baere et al., 1999 [PubMed 10600115]). [supplied by OMIM, Mar 2008]
Synonyms	CGI-68; LCMT; PPMT1
Reference Data
Protein Pathways	Androgen and estrogen metabolism, Histidine metabolism, Selenoamino acid metabolism, Tyrosine metabolism

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