ADH1B Mouse Monoclonal Antibody (Biotin conjugated) [Clone ID: OTI4F12]

Specifications

Product Data
Clone Name	OTI4F12
Applications	FC, IF, IHC, WB
Recommend Dilution	WB 1:500, IHC 1:150, IF 1:100, FLOW 1:100
Reactivity	Human, Dog, Rat
Host	Mouse
Clonality	Monoclonal
Immunogen	Full length human recombinant protein of human ADH1B (NP_000659) produced in HEK293T cell.
Isotype	IgG2a
Formulation	PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Concentration	0.5 mg/ml
Purification	Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation	Biotin
Storage Condition	Store at -20°C as received.
Predicted Protein Size	39.7 kDa
Gene Name	alcohol dehydrogenase 1B (class I), beta polypeptide
Database Link	NP_000659 Entrez Gene 125 Human UniProt ID P00325
Background	The protein encoded by this gene is a member of the alcohol dehydrogenase family. Members of this enzyme family metabolize a wide variety of substrates, including ethanol, retinol, other aliphatic alcohols, hydroxysteroids, and lipid peroxidation products. This encoded protein, consisting of several homo- and heterodimers of alpha, beta, and gamma subunits, exhibits high activity for ethanol oxidation and plays a major role in ethanol catabolism. Three genes encoding alpha, beta and gamma subunits are tandemly organized in a genomic segment as a gene cluster. [provided by RefSeq]
Synonyms	ADH2; HEL-S-117
Reference Data
Protein Families	Druggable Genome
Protein Pathways	Drug metabolism - cytochrome P450, Fatty acid metabolism, Glycolysis / Gluconeogenesis, Metabolic pathways, Metabolism of xenobiotics by cytochrome P450, Retinol metabolism, Tyrosine metabolism

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