BCAR1 Mouse Monoclonal Antibody [Clone ID: OTI1B1]

Specifications

Product Data
Clone Name	OTI1B1
Applications	FC, IF, IHC, WB
Recommend Dilution	WB 1:500~2000, IHC 1:150, IF 1:100, FLOW 1:100
Reactivity	Human, Dog, Rat, Monkey, Mouse
Host	Mouse
Clonality	Monoclonal
Immunogen	Full length human recombinant protein of human BCAR1 (NP_055382) produced in HEK293T cell.
Isotype	IgG1
Formulation	PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Concentration	0.74 mg/ml
Purification	Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	93.2 kDa
Gene Name	BCAR1 scaffold protein, Cas family member
Database Link	NP_055382 Entrez Gene 12927 MouseEntrez Gene 25414 RatEntrez Gene 479648 DogEntrez Gene 713965 MonkeyEntrez Gene 9564 Human UniProt ID P56945
Background	BCAR1, or CAS, is an Src (MIM 190090) family kinase substrate involved in various cellular events, including migration, survival, transformation, and invasion (Sawada et al., 2006 [PubMed 17129785]). [supplied by OMIM]
Synonyms	CAS; CAS1; CASS1; CRKAS; P130Cas
Reference Data
Protein Families	Druggable Genome
Protein Pathways	Chemokine signaling pathway, Focal adhesion, Leukocyte transendothelial migration, Regulation of actin cytoskeleton

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