Beclin 1 (BECN1) Mouse Monoclonal Antibody (Biotin conjugated) [Clone ID: OTI3H8]

Specifications

Product Data
Clone Name	OTI3H8
Applications	FC, IF, IHC, WB
Recommend Dilution	WB 1:500~2000, IHC 1:150, IF 1:100, FLOW 1:100
Reactivity	Human, Rat, Monkey, Mouse
Host	Mouse
Clonality	Monoclonal
Immunogen	Full length human recombinant protein of human BECN1 (NP_003757) produced in HEK293T cell.
Isotype	IgG2a
Formulation	PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Concentration	0.5 mg/ml
Purification	Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation	Biotin
Storage Condition	Store at -20°C as received.
Predicted Protein Size	51.7 kDa
Gene Name	beclin 1
Database Link	NP_003757 Entrez Gene 56208 MouseEntrez Gene 114558 RatEntrez Gene 711649 MonkeyEntrez Gene 8678 Human UniProt ID Q14457
Background	Beclin-1 participates in the regulation of autophagy and has an important role in development, tumorigenesis, and neurodegeneration (Zhong et al., 2009 [PubMed 19270693]). [supplied by OMIM, Jul 2010]
Synonyms	ATG6; beclin1; VPS30
Reference Data
Protein Families	Druggable Genome
Protein Pathways	Regulation of autophagy

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