Aquaporin 1 (AQP1) Mouse Monoclonal Antibody [Clone ID: OTI2D10]

Specifications

Product Data
Clone Name	OTI2D10
Applications	FC, IF, IHC, WB
Recommend Dilution	WB 1:2000, IHC 1:150, IF 1:100, FLOW 1:100
Reactivity	Human
Host	Mouse
Clonality	Monoclonal
Immunogen	Full length human recombinant protein of human AQP1 (NP_932766) produced in HEK293T cell.
Isotype	IgG1
Formulation	PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Concentration	0.47 mg/ml
Purification	Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	28.3 kDa
Gene Name	aquaporin 1 (Colton blood group)
Database Link	NP_932766 Entrez Gene 358 Human UniProt ID P29972
Background	Aquaporins are a family of small integral membrane proteins related to the major intrinsic protein (MIP or AQP0). This gene encodes an aquaporin which functions as a molecular water channel protein. It is a homotetramer with 6 bilayer spanning domains and N-glycosylation sites. The protein physically resembles channel proteins and is abundant in erythrocytes and renal tubes. The gene encoding this aquaporin is a possible candidate for disorders involving imbalance in ocular fluid movement. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]
Synonyms	AQP-CHIP; CHIP28; CO
Reference Data
Protein Families	Druggable Genome, Ion Channels: Other, Transmembrane

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