PPM1G Mouse Monoclonal Antibody [Clone ID: OTI1C12]

Specifications

Product Data
Clone Name	OTI1C12
Applications	IF, WB
Recommend Dilution	WB 1:500~2000, IF 1:100
Reactivity	Human, Dog, Mouse, Rat
Host	Mouse
Clonality	Monoclonal
Immunogen	Full length human recombinant protein of human PPM1G (NP_817092) produced in HEK293T cell.
Isotype	IgG2a
Formulation	PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Concentration	1 mg/ml
Purification	Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	59.1 kDa
Gene Name	protein phosphatase, Mg2+/Mn2+ dependent 1G
Database Link	NP_817092 Entrez Gene 475703 DogEntrez Gene 5496 Human UniProt ID O15355
Background	The protein encoded by this gene is a member of the PP2C family of Ser/Thr protein phosphatases. PP2C family members are known to be negative regulators of cell stress response pathways. This phosphatase is found to be responsible for the dephosphorylation of Pre-mRNA splicing factors, which is important for the formation of functional spliceosome. Studies of a similar gene in mice suggested a role of this phosphatase in regulating cell cycle progression. [provided by RefSeq, Apr 2010]
Synonyms	PP2CG; PP2CGAMMA; PPP2CG
Reference Data
Protein Families	Druggable Genome, Phosphatase

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