LMAN1 Mouse Monoclonal Antibody [Clone ID: OTI1A8]

Specifications

Product Data
Clone Name	OTI1A8
Applications	FC, IF, IHC, Simple Western, WB
Recommend Dilution	WB 1:200~500, IHC 1:150, IF 1:100, FLOW 1:100 ; Simple Western 1:20-1:50
Reactivity	Human, Dog, Rat, Monkey, Mouse
Host	Mouse
Clonality	Monoclonal
Immunogen	Full length human recombinant protein of human LMAN1 (NP_005561) produced in HEK293T cell.
Isotype	IgG1
Formulation	PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Concentration	1 mg/ml
Purification	Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	54.2 kDa
Gene Name	lectin, mannose binding 1
Database Link	NP_005561 Entrez Gene 70361 MouseEntrez Gene 116666 RatEntrez Gene 476186 DogEntrez Gene 697449 MonkeyEntrez Gene 3998 Human UniProt ID P49257
Background	The protein encoded by this gene is a type I integral membrane protein localized in the intermediate region between the endoplasmic reticulum and the Golgi, presumably recycling between the two compartments. The protein is a mannose-specific lectin and is a member of a novel family of plant lectin homologs in the secretory pathway of animal cells. Mutations in the gene are associated with a coagulation defect. Using positional cloning, the gene was identified as the disease gene leading to combined factor V-factor VIII deficiency, a rare, autosomal recessive disorder in which both coagulation factors V and VIII are diminished. [provided by RefSeq]
Synonyms	ERGIC-53; ERGIC53; F5F8D; FMFD1; gp58; MCFD1; MR60
Reference Data
Protein Families	Druggable Genome, Transmembrane

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