mu Crystallin (CRYM) Mouse Monoclonal Antibody [Clone ID: OTI1B5]

Specifications

Product Data
Clone Name	OTI1B5
Applications	IF, IHC, WB
Recommend Dilution	WB: 1:200 - 1:1000, IHC 1:300, IF 1:100
Reactivity	Human, Mouse, Rat
Host	Mouse
Clonality	Monoclonal
Immunogen	Full length human recombinant protein of human CRYM (NP_001879) produced in HEK293T cell.
Isotype	IgG2a
Formulation	PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Concentration	0.58 mg/ml
Purification	Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	33.6 kDa
Gene Name	crystallin mu
Database Link	NP_001879 Entrez Gene 12971 MouseEntrez Gene 117024 RatEntrez Gene 1428 Human UniProt ID Q14894
Background	Crystallins are separated into two classes: taxon-specific and ubiquitous. The former class is also called phylogenetically-restricted crystallins. The latter class constitutes the major proteins of vertebrate eye lens and maintains the transparency and refractive index of the lens. This gene encodes a taxon-specific crystallin protein that binds NADPH and has sequence similarity to bacterial ornithine cyclodeaminases. The encoded protein does not perform a structural role in lens tissue, and instead it binds thyroid hormone for possible regulatory or developmental roles. Mutations in this gene have been associated with autosomal dominant non-syndromic deafness. Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq]
Synonyms	DFNA40; THBP
Reference Data

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