HIBCH Mouse Monoclonal Antibody [Clone ID: OTI4G1]

Specifications

Product Data
Clone Name	OTI4G1
Applications	FC, IF, WB
Recommend Dilution	WB 1:500~2000, IF 1:100, FLOW 1:100
Reactivity	Human, Dog, Rat, Monkey
Host	Mouse
Clonality	Monoclonal
Immunogen	Full length human recombinant protein of human HIBCH (NP_055177) produced in HEK293T cell.
Isotype	IgG2b
Formulation	PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Concentration	0.7 mg/ml
Purification	Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	39.4 kDa
Gene Name	3-hydroxyisobutyryl-CoA hydrolase
Database Link	NP_055177 Entrez Gene 301384 RatEntrez Gene 607040 DogEntrez Gene 713951 MonkeyEntrez Gene 26275 Human UniProt ID Q6NVY1
Background	This gene encodes the enzyme responsible for hydrolysis of both HIBYL-CoA and beta-hydroxypropionyl-CoA. Mutations in this gene have been associated with 3-hyroxyisobutyryl-CoA hydrolase deficiency. Alternative splicing results in multiple transcript variants.
Synonyms	HIBYLCOAH
Reference Data
Protein Pathways	beta-Alanine metabolism, Metabolic pathways, Propanoate metabolism, Valine, leucine and isoleucine degradation

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