GNMT Mouse Monoclonal Antibody [Clone ID: OTI8A3]

Specifications

Product Data
Clone Name	OTI8A3
Applications	FC, WB
Recommend Dilution	WB: 1:200 - 1:1000, Flow 1:100
Reactivity	Human
Host	Mouse
Clonality	Monoclonal
Immunogen	Full length human recombinant protein of human GNMT (NP_061833) produced in HEK293T cell.
Isotype	IgG3
Formulation	PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Concentration	1 mg/ml
Purification	Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	32.6 kDa
Gene Name	glycine N-methyltransferase
Database Link	NP_061833 Entrez Gene 27232 Human UniProt ID Q14749
Background	The protein encoded by this gene is an enzyme that catalyzes the conversion of S-adenosyl-L-methionine (along with glycine) to S-adenosyl-L-homocysteine and sarcosine. The encoded protein is found in the cytoplasm and acts as a homotetramer. Defects in this gene are a cause of GNMT deficiency (hypermethioninemia).
Synonyms	glycine N-methyltransferase; OTTHUMP00000016412
Reference Data
Protein Families	Druggable Genome
Protein Pathways	Glycine, serine and threonine metabolism

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