PDE4A Mouse Monoclonal Antibody (Biotin conjugated) [Clone ID: OTI1C8]

Specifications

Product Data
Clone Name	OTI1C8
Applications	FC, IF, IHC, WB
Recommend Dilution	WB 1:2000, IHC 1:50, IF 1:100, FLOW 1:100
Reactivity	Human, Rat
Host	Mouse
Clonality	Monoclonal
Immunogen	Full length human recombinant protein of human PDE4A (NP_006193) produced in HEK293T cell.
Isotype	IgG1
Formulation	PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Concentration	0.5 mg/ml
Purification	Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation	Biotin
Storage Condition	Store at -20°C as received.
Predicted Protein Size	72.0 kDa
Gene Name	phosphodiesterase 4A
Database Link	NP_006193 Entrez Gene 5141 Human UniProt ID P27815
Background	Cyclic nucleotides are important second messengers that regulate and mediate a number of cellular responses to extracellular signals, such as hormones, light, and neurotransmitters. Cyclic nucleotide phosphodiesterases (PDEs) regulate the cellular concentrations of cyclic nucleotides and thereby play a role in signal transduction. PDE4A is a class IV cAMP-specific PDE
Synonyms	DPDE2; PDE4; PDE46
Reference Data
Protein Families	Druggable Genome
Protein Pathways	Progesterone-mediated oocyte maturation, Purine metabolism

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