FRA1 (FOSL1) Mouse Monoclonal Antibody [Clone ID: OTI12F9]

Specifications

Product Data
Clone Name	OTI12F9
Applications	IHC, WB
Recommend Dilution	WB 1:2000, IHC 1:50
Reactivity	Human, Mouse, Rat
Host	Mouse
Clonality	Monoclonal
Immunogen	Full-length protein expressed in 293T cell transfected with human FOSL1 expression vector
Isotype	IgG2b
Formulation	PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Concentration	1.1 mg/ml
Purification	Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	29.4 kDa
Gene Name	FOS like 1, AP-1 transcription factor subunit
Database Link	NP_005429 Entrez Gene 14283 MouseEntrez Gene 25445 RatEntrez Gene 8061 Human UniProt ID P15407
Background	The Fos gene family consists of 4 members: FOS, FOSB, FOSL1, and FOSL2. These genes encode leucine zipper proteins that can dimerize with proteins of the JUN family, thereby forming the transcription factor complex AP-1. As such, the FOS proteins have been implicated as regulators of cell proliferation, differentiation, and transformation.
Synonyms	FRA; fra-1; FRA1
Reference Data
Protein Families	Druggable Genome, Transcription Factors
Protein Pathways	Wnt signaling pathway

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