STK3 Mouse Monoclonal Antibody [Clone ID: OTI4G10]

Specifications

Product Data
Clone Name	OTI4G10
Applications	IHC, WB
Recommend Dilution	WB 1:2000; IHC 1:50
Reactivity	Human, Monkey, Dog, Mouse, Rat
Host	Mouse
Clonality	Monoclonal
Immunogen	Full-length protein expressed in 293T cell transfected with human STK3 expression vector
Isotype	IgG2b
Formulation	PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Concentration	1 mg/ml
Purification	Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	56.3 kDa
Gene Name	serine/threonine kinase 3
Database Link	NP_006272 Entrez Gene 56274 MouseEntrez Gene 65189 RatEntrez Gene 475045 DogEntrez Gene 707425 MonkeyEntrez Gene 6788 Human UniProt ID Q13188
Background	Protein kinase activation is a frequent response of cells to treatment with growth factors,chemicals, heat shock, or apoptosis-inducing agents. This protein kinase activation presumably allows cells to resist unfavorable environmental conditions. The yeast ' sterile 20'(Ste20) kinase acts upstream of the mitogen-activated protein kinase (MAPK) cascade that is activated under a variety of stress conditions. MST2 was identified as a kinase that is activated by the proapoptotic agents straurosporine and FAS ligand
Synonyms	KRS1; MST2
Reference Data
Protein Families	Druggable Genome, Protein Kinase
Protein Pathways	MAPK signaling pathway

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