PLK1 Mouse Monoclonal Antibody [Clone ID: OTI8C12]

Specifications

Product Data
Clone Name	OTI8C12
Applications	FC, IF, IP
Recommend Dilution	IF 1:100, FLOW 1:100, IP 2ug/500ul
Reactivity	Human, Dog, Monkey, Mouse, Rat
Host	Mouse
Clonality	Monoclonal
Immunogen	Full-length protein expressed in 293T cell transfected with human PLK1 expression vector
Isotype	IgG1
Formulation	PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Concentration	0.96 mg/ml
Purification	Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	68.1 kDa
Gene Name	polo like kinase 1
Database Link	NP_005021 Entrez Gene 18817 MouseEntrez Gene 25515 RatEntrez Gene 489971 DogEntrez Gene 697686 MonkeyEntrez Gene 5347 Human UniProt ID P53350
Background	Serine/threonine-protein kinase that performs several important functions throughout M phase of the cell cycle, including the regulation of centrosome maturation and spindle assembly,the removal of cohesins from chromosome arms, the inactivation of APC/C inhibitors, and the regulation of mitotic exit and cytokinesis
Synonyms	PLK; STPK13
Reference Data
Protein Families	Druggable Genome, Protein Kinase
Protein Pathways	Cell cycle, Oocyte meiosis, Progesterone-mediated oocyte maturation

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