Oncostatin M (OSM) Mouse Monoclonal Antibody [Clone ID: OTI2B6]

Specifications

Product Data
Clone Name	OTI2B6
Applications	IHC
Recommend Dilution	IHC 1:50
Reactivity	Human
Host	Mouse
Clonality	Monoclonal
Immunogen	Recombinant protein expressed in E.coli corresponding to amino acids 25-252 of human OSM
Isotype	IgG1
Formulation	PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Concentration	1 mg/ml
Purification	Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	25.7 kDa
Gene Name	oncostatin M
Database Link	NP_065391 Entrez Gene 5008 Human UniProt ID P13725
Background	Oncostatin M is a member of a cytokine family that includes leukemia-inhibitory factor, granulocyte colony-stimulating factor, and interleukin 6. This gene encodes a growth regulator which inhibits the proliferation of a number of tumor cell lines. It regulates cytokine production, including IL-6, G-CSF and GM-CSF from endothelial cells
Synonyms	MGC20461
Reference Data
Protein Families	Druggable Genome, ES Cell Differentiation/IPS, Secreted Protein, Stem cell relevant signaling - DSL/Notch pathway, Stem cell relevant signaling - JAK/STAT signaling pathway
Protein Pathways	Cytokine-cytokine receptor interaction, Jak-STAT signaling pathway

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