Neurogenin3 (NEUROG3) Mouse Monoclonal Antibody [Clone ID: OTI5A8]

Specifications

Product Data
Clone Name	OTI5A8
Applications	IHC, IP
Recommend Dilution	IHC: 1:150
Reactivity	Human
Host	Mouse
Clonality	Monoclonal
Immunogen	Recombinant fragment expressed in E.coli corresponding to amino acids 1-214of human Ngn3
Isotype	IgG2b
Formulation	PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Concentration	1 mg/ml
Purification	Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	22.9 kDa
Gene Name	neurogenin 3
Database Link	NP_066279 Entrez Gene 50674 Human UniProt ID Q9Y4Z2
Background	Neurogenin-3 (NEUROG3) is expressed in endocrine progenitor cells and is required for endocrine cell development in the pancreas and intestine (Wang et al., 2006 [PubMed 16855267]). It belongs to a family of basic helix-loop-helix transcription factors involved in the determination of neural precursor cells in the neuroectoderm (Gradwohl et al., 2000 [PubMed 10677506]).[
Synonyms	Atoh5; bHLHa7; Math4B; NGN-3; ngn3
Reference Data
Protein Families	ES Cell Differentiation/IPS
Protein Pathways	Maturity onset diabetes of the young

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