alpha 1 Antitrypsin (SERPINA1) Mouse Monoclonal Antibody [Clone ID: OTI1C2]

Specifications

Product Data
Clone Name	OTI1C2
Applications	FC, IHC, WB
Recommend Dilution	WB 1:500~1000, IHC 1:50, FLOW 1:100
Reactivity	Human
Host	Mouse
Clonality	Monoclonal
Immunogen	Human recombinant protein fragment corresponding to amino acids 26-418 of human A1AT (NP_000286) produced in E.coli.
Isotype	IgG2b
Formulation	PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Concentration	1 mg/ml
Purification	Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	46.6 kDa
Gene Name	serpin family A member 1
Database Link	NP_000286 Entrez Gene 5265 Human UniProt ID P01009
Background	A1AT is secreted and is a serine protease inhibitor whose targets include elastase, plasmin, thrombin, trypsin, chymotrypsin, and plasminogen activator. Defects in A1AT gene can cause emphysema or liver disease. Several transcript variants encoding the same protein have been found for this gene.
Synonyms	A1A; A1AT; AAT; alpha1AT; PI; PI1; PRO2275
Reference Data
Protein Families	Druggable Genome, ES Cell Differentiation/IPS, Secreted Protein
Protein Pathways	Complement and coagulation cascades

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