Cytokeratin 8 (KRT8) Mouse Monoclonal Antibody (HRP conjugated) [Clone ID: OTI2E4]

Specifications

Product Data
Clone Name	OTI2E4
Applications	IF, IHC, WB
Recommend Dilution	WB 1:500~1000, IHC 1:50, IF 1:50~100
Reactivity	Human, Mouse, Rat
Host	Mouse
Clonality	Monoclonal
Immunogen	Human recombinant protein fragment corresponding to amino acids 91-381 of human CK8 (NP_002264) produced in E.coli.
Isotype	IgG1
Formulation	PBS (pH 7.3) containing 1% BSA, 50% glycerol.
Concentration	0.5 mg/ml
Purification	Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation	HRP
Storage Condition	Store at -20°C as received.
Predicted Protein Size	53.5 kDa
Gene Name	keratin 8
Database Link	NP_002264 Entrez Gene 16691 MouseEntrez Gene 25626 RatEntrez Gene 3856 Human UniProt ID P05787
Background	Keratin 8 is a member of the type II keratin family clustered on the long arm of chromosome 12. Type I and type II keratins heteropolymerize to form intermediate-sized filaments in the cytoplasm of epithelial cells. The product of this gene typically dimerizes with keratin 18 to form an intermediate filament in simple single-layered epithelial cells. This protein plays a role in maintaining cellular structural integrity and also functions in signal transduction and cellular differentiation. Mutations in this gene cause cryptogenic cirrhosis.
Synonyms	CARD2; CK-8; CK8; CYK8; K2C8; K8; KO
Reference Data
Protein Families	Druggable Genome

*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.