Abca1 Rat Monoclonal Antibody [Clone ID: 5A1-1422]

Specifications

Product Data
Clone Name	5A1-1422
Applications	FC, IF
Host	Rat
Clonality	Monoclonal
Immunogen	ABCA1 transfected HeLa cells.
Specificity	ABCA1
Isotype	IgG2a
Formulation	Phosphate buffered saline containing 0.09%Sodium Azide (NaN3) Label: ALEXA FLUOR® 488,ALEXA FLUOR® 647,FITC,Purified,RPE State: Purified IgG prepared by affinity chromatography on Protein G from tissue culture supernatant Purified IgG - liquid
Concentration	lot specific
Conjugation	Unconjugated
Storage Condition	+4°C, -20°C if preferred
Gene Name	ATP-binding cassette, sub-family A (ABC1), member 1
Database Link	UniProt ID P41233
Background	Rat anti Mouse ABCA1 antibody, clone 5A1.1422 recognizes murine adenosine triphosphate (ATP) Binding cassette transporter 1 (ABCA1). The ABC transporters are a large family of conserved proteins that transport a wide variety of molecules across cellular membranes. ABCA1 is a member of the ABC-A sub-family, which acts as a lipid translocator. The molecule was originally identified as a scavenger receptor on macrophages and research shows that ABCA1 also plays a major role in cholesterol metabolism. ABCA1 may play an important role in protecting against cardiovascular disease.Mutations in ABCA1 gene have been associated with Tangier disease, a genetic disorder of lipid metabolism, and the more common Familial HDL deficiency, peresenting with many of the same symproms.
Synonyms	ABC-1; ABC1; CERP; FLJ14958; HDLDT1; membrane-bound; MGC164864; MGC165011; TGD
Reference Data

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