Isocitrate dehydrogenase (IDH1) Mouse Monoclonal Antibody [Clone ID: OTI2H9]
CAT＃: TA400009
Anti-IDH1 mouse mAb, clone OTI2H9, HRP conjugated
Conjugation: Unconjugated Biotin DyLight488
View other "OTI2H9" antibodies (7)
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CNY 3790.00
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Specifications
| Product Data | |
| Clone Name | OTI2H9 |
| Applications | WB |
| Recommend Dilution | WB: 1:1000 |
| Reactivity | Human |
| Host | Mouse |
| Clonality | Monoclonal |
| Immunogen | Full-length protein expressed in 293T cell transfected with human IDH1 expression vector |
| Isotype | IgG1 |
| Formulation | PBS (pH7.4) containing 50% glycerol, 0.1% BSA |
| Concentration | 0.5 mg/ml |
| Purification | Purified from mouse ascites fluids by affinity chromatography |
| Conjugation | HRP |
| Storage Condition | Store at -20°C as received. |
| Predicted Protein Size | 46.7 kDa |
| Gene Name | isocitrate dehydrogenase (NADP(+)) 1 |
| Database Link | |
| Background | Isocitrate dehydrogenases catalyze the oxidative decarboxylation of isocitrate to 2-oxoglutarate. These enzymes belong to two distinct subclasses, one of which utilizes NAD(+) as the electron acceptor and the other NADP(+). Five isocitrate dehydrogenases have been reported: three NAD(+)-dependent isocitrate dehydrogenases, which localize to the mitochondrial matrix, and two NADP(+)-dependent isocitrate dehydrogenases, one of which is mitochondrial and the other predominantly cytosolic. Each NADP(+)-dependent isozyme is a homodimer. The protein encoded by this gene is the NADP(+)-dependent isocitrate dehydrogenase found in the cytoplasm and peroxisomes. It contains the PTS-1 peroxisomal targeting signal sequence. The presence of this enzyme in peroxisomes suggests roles in the regeneration of NADPH for intraperoxisomal reductions, such as the conversion of 2, 4-dienoyl-CoAs to 3-enoyl-CoAs, as well as in peroxisomal reactions that consume 2-oxoglutarate, namely the alpha-hydroxylation of phytanic acid. The cytoplasmic enzyme serves a significant role in cytoplasmic NADPH production. |
| Synonyms | HEL-216; HEL-S-26; IDCD; IDH; IDP; IDPC; PICD |
| Reference Data | |
| Protein Pathways | Citrate cycle (TCA cycle), Glutathione metabolism, Metabolic pathways |
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Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| CF500610 | Carrier-free (BSA/glycerol-free) IDH1 mouse monoclonal antibody, clone OTI2H9 (formerly 2H9) |
CNY 3999.00 |
|
| TA400008 | Anti-IDH1 mouse mAb, clone OTI2H9, Biotinylated |
CNY 3790.00 |
|
| TA400028 | Anti-IDH1 mouse mAb, clone OTI2H9, DyLight488 conjugated |
CNY 3790.00 |
|
| TA500610 | Anti-IDH1 (Isocitrate Dehydrogenase 1) mouse monoclonal antibody, clone OTI2H9 (formerly 2H9) |
CNY 1999.00 |
|
| TA500610S | Anti-IDH1 (Isocitrate Dehydrogenase 1) mouse monoclonal antibody, clone OTI2H9 (formerly 2H9) |
CNY 800.00 |
|
| TA600198 | IDH1 mouse monoclonal capture antibody, validated for ELISA and Luminex assays |
CNY 2600.00 |
|
| TA700198 | IDH1 biotinylated mouse monoclonal detection antibody, validated for ELISA and Luminex assays |
CNY 2700.00 |
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