MUC16 Rabbit Monoclonal Antibody [Clone ID: 20000]

Specifications

Product Data
Clone Name	20000
Applications	ELISA, IHC, WB
Reactivity	Human
Modifications	This chimeric rabbit antibody was made using the variable domain sequences of the original Mouse IgG2b format for improved compatibility with existing reagents assays and techniques.
Host	Rabbit
Clonality	Monoclonal
Immunogen	The original antibody was generated by immunizing mice with recombinant protein CA125.
Specificity	The original antibody is specific for CA125. CA125 is thought to provide a protective, lubricating barrier against particles and infectious agents at mucosal surfaces. This antigen that is the basis for a widely used serum assay for the monitoring of patients with ovarian epithelial cancer. The antibody 20E3 and the commercial antibody TA347 were used to stain ovarian slurry adenocarcinoma and ovarian mucous adenocarcinoma in immunohistochemistry. Results showed the antibody specificity is comparable to the commercial antibody. Further, the staining intensity of the antibody 20E3 was higher than the commercial antibody (CN113061186A).
Formulation	PBS with 0.02% Proclin 300.
Concentration	lot specific
Conjugation	Unconjugated
Storage Condition	Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at -20⁰C.
Database Link	UniProt ID Q8WXI7
Synonyms	CA-125; CGMCC NO 20773; MUC-16; Mucin-16; Ovarian cancer-related tumor marker CA125; Ovarian carcinoma antigen CA125; TA347
Reference Data

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