CEBP Alpha (CEBPA) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	WB
Recommend Dilution	WB: 1:500~1:1000 IHC: 1:50~1:200
Reactivity	Human, Mouse, Rat
Host	Rabbit
Clonality	Polyclonal
Immunogen	Synthetic phosphopeptide derived from human C/EBP α around the phosphorylation site of Serine 21.
Specificity	p-C/EBP α (S21) polyclonal antibody detects endogenous levels of C/EBP α protein only when phosphorylated at Ser21.
Isotype	IgG
Formulation	Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Concentration	1mg/ml
Conjugation	Unconjugated
Storage Condition	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Predicted Protein Size	~ 30,45 kDa
Gene Name	CCAAT/enhancer binding protein alpha
Database Link	Entrez Gene 1050 Human UniProt ID P49715
Background	C/EBP α regulates gene expression in a variety of tissues including liver, adipose, lung and intestine. C/EBP α is a basic region/leucine zipper transcription factor selectively expressed during the differentiation of liver, adipose tissue, blood cells and the endocrine pancreas. C/EBP α uses a bipartite structural motif to bind DNA and appears to function exclusively in terminally differentiated, growtharrested cells. In the liver, C/EBP α is a transactivator of several genes, which are regulated by growth hormone. Growth hormone enhances not only the levels of C/EBP α mRNA and protein, but also the DNA-binding activity of C/EBP α. C/EBP α functions as an important transcription factor that regulates different genes, including Prolactin gene expression.
Synonyms	C/EBP alpha; C/EBP α; C/EBPα; CCAAT/enhancer-binding protein alpha; CEBPA
Note	For research use only, not for use in diagnostic procedure.
Reference Data

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