Angiopoietin like 7 (ANGPTL7) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	WB
Recommend Dilution	WB: 1:500~1:1000 IHC: 1:50~1:200
Reactivity	Human, Mouse, Rat
Host	Rabbit
Clonality	Polyclonal
Immunogen	Synthetic peptide, corresponding to amino acids 321-370 of Human Angptl7.
Specificity	Angptl7 (P346) polyclonal antibody detects endogenous levels of Angptl7 protein.
Isotype	IgG
Formulation	Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Concentration	1mg/ml
Conjugation	Unconjugated
Storage Condition	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Predicted Protein Size	~ 40 kDa
Gene Name	angiopoietin like 7
Database Link	Entrez Gene 10218 Human UniProt ID O43827
Background	Angptl7 (angiopoietin-like 7), alternately known as cornea-derived transcript 6 protein (CDT6) or AngX, is a 346 amino acid secreted protein that is expressed specifically in the stromal layer of cornea. Angptl7 forms disulfide-linked homotetramers via coiled-coil interactions and contains one fibrinogen C-terminal domain. Overexpressed in patients with glaucoma, Angptl7 serves as a potential therapeutic target for glaucoma and has been found to increase collagen expression. The gene encoding Angptl7 maps to human chromosome 1, which spans 260 million base pairs, contains over 3,000 genes and comprises nearly 8% of the human genome.
Synonyms	Angiopoietin-like factor; Angiopoietin-like protein 7; Angiopoietin-related protein 7; ANGPTL7; CDT6; Cornea-derived transcript 6 protein; ORF Names: UNQ313/PRO356
Note	For research use only, not for use in diagnostic procedure.
Reference Data

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