Lysophospholipase 1 (LYPLA1) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	WB
Recommend Dilution	WB: 1:500~1:1000 IHC: 1:50~1:200
Reactivity	Human, Mouse, Rat
Host	Rabbit
Clonality	Polyclonal
Immunogen	Synthetic peptide, corresponding to amino acids 61-110 of Human LYPLA1.
Specificity	LYPLA1 (K90) polyclonal antibody detects endogenous levels of LYPLA1 protein.
Isotype	IgG
Formulation	Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Concentration	1mg/ml
Conjugation	Unconjugated
Storage Condition	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Predicted Protein Size	~ 25 kDa
Gene Name	lysophospholipase I
Database Link	Entrez Gene 10434 Human UniProt ID O75608
Background	Acyl-protein thioesterase 1 (APT1, Lysophospholipase 1) is a member of a family of critical enzymes, lysophospholipases, that act on biological membranes to regulate the multifunctional lysophospholipids. APT1 hydrolyzes fatty acids from S-acylated cysteine residues in proteins such as trimeric G alpha proteins or HRAS. The role of APT1 in regulating lysophospholipids is important because increased levels of lysophospholipids are detected in a variety of diseases, including atherosclerosis and hyperlipidemia. Regulated expression of acyl-protein thioesterase by PKC has been suggested to have important implications for signal transduction processes.
Synonyms	Acyl-protein thioesterase 1; APT-1; APT1; hAPT1; LPL-I; LPL1; LYPLA1; Lysophospholipase 1; Lysophospholipase I; LysoPLA I
Note	For research use only, not for use in diagnostic procedure.
Reference Data

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