Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	WB
Recommend Dilution	WB: 1:500~1:1000
Reactivity	Human, Mouse, Rat
Host	Rabbit
Clonality	Polyclonal
Immunogen	Synthetic peptide, corresponding to amino acids 81-130 of Human TCR β.
Specificity	TCR β (K115) polyclonal antibody detects endogenous levels of TCR β protein.
Isotype	IgG
Formulation	Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Concentration	1mg/ml
Conjugation	Unconjugated
Storage Condition	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Predicted Protein Size	~ 19 kDa
Database Link	UniProt ID P01850
Background	TCR (T cell antigen receptor) recognizes foreign antigens and translates such recognition events into intracellular signals that elicit a change in the cell from a dormant to an activated state. TCR is a heterodimer composed of either alpha and beta or gamma and delta chains. The vast majority of circulating T cells (95%) express the alpha/beta heterodimer while roughly 2-5% express the gamma/delta heterodimer. CD3 chains and the CD4 or CD8 coreceptors are also required for efficient signal transduction through the TCR.
Synonyms	T-cell receptor beta-1 chain C region; TRBC1
Note	For research use only, not for use in diagnostic procedure.
Reference Data

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