ULK1 Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	WB
Recommend Dilution	WB: 1:500~1:1000
Reactivity	Human, Mouse, Rat
Host	Rabbit
Clonality	Polyclonal
Immunogen	Synthetic phosphopeptide derived from human ULK1 around the phosphorylation site of Ser555.
Specificity	ULK1 (phospho-Ser555) polyclonal antibody detects endogenous levels of ULK1 protein only when phosphorylated at Ser555.
Formulation	Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Concentration	1mg/ml
Conjugation	Unconjugated
Storage Condition	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Predicted Protein Size	~ 150 kDa
Gene Name	unc-51 like autophagy activating kinase 1
Database Link	Entrez Gene 8408 Human UniProt ID O75385
Background	ULK1 and ULK2 (for UNC-51-like kinase) encode similar amino-terminal serine/threonine kinase domains, a proline/serine-rich (PS) domain, and a species conserved carboxyl-terminal domain. Both share homology with the UNC-51 kinase from Caenorhabditis elegans and the APG1 kinase in yeast, which are involved in axonal extension and growth, and autophagy, respectively. ULK1 and ULK2 are thought to auto-phosphorylate the PS domain in vitro, and the significant homology among vertebrates suggest that ULK1 and ULK2 are involved in the regulation of fundamental biological processes.
Synonyms	ATG1; Autophagy-related protein 1 homolog; KIAA0722; Serine/threonine-protein kinase ULK1; ULK1; Unc-51-like kinase 1
Note	For research use only, not for use in diagnostic procedure.
Reference Data

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