Raptor (RPTOR) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	WB
Recommend Dilution	WB: 1:500~1:1000
Reactivity	Human, Mouse
Host	Rabbit
Clonality	Polyclonal
Immunogen	Synthetic phosphopeptide derived from human Raptor around the phosphorylation site of Ser792.
Specificity	A phospho specific peptide corresponding to residues surrounding Ser792 of human RPTOR
Isotype	IgG
Formulation	Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Concentration	1mg/ml
Conjugation	Unconjugated
Storage Condition	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Predicted Protein Size	~ 150 kDa
Gene Name	regulatory associated protein of MTOR complex 1
Database Link	Entrez Gene 57521 Human UniProt ID Q8N122
Background	Regulatory associated protein of FRAP, also designated Raptor, is a binding partner for mammalian target of rapamycin kinase (FRAP), and is essential for FRAP signalling in vivo. Raptor binding to FRAP is critical for FRAP-catalysed substrate phosphorylation of 4E-BP1. The raptor-FRAP complex is nutrient-sensitive and is important for a mechanism by which cells coordinate cell growth and size with changing environmental conditions. Raptor serves as a negative regulator of FRAP kinase activity under nutrient-deprived conditions and is an important component in the FRAP pathway. Raptor is highly expressed in skeletal muscle and to a lesser extent in brain, kidney, lung and placenta.
Synonyms	KIAA1303; p150 target of rapamycin (TOR)-scaffold protein; RAPTOR; Raptor; Regulatory-associated protein of mTOR; RPTOR
Note	For research use only, not for use in diagnostic procedure.
Reference Data

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