ITLN1 Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	WB
Recommend Dilution	WB: 1:1000~1:2000 IHC: 1:50~1:200
Reactivity	Human
Host	Rabbit
Clonality	Polyclonal
Immunogen	Synthetic peptide, corresponding to Human LFR.
Specificity	LFR polyclonal antibody detects endogenous levels of LFR protein.
Isotype	IgG
Formulation	Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Concentration	1mg/ml
Conjugation	Unconjugated
Storage Condition	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Predicted Protein Size	~ 34 kDa
Gene Name	intelectin 1
Database Link	Entrez Gene 55600 Human UniProt ID Q8WWA0
Background	Intelectin-1, also known as ITLN1, INTL, Omentin or LFR, is a 313 amino acid protein that contains one fibrinogen C-terminal domain and is either secreted or lipid-anchored to the cell membrane. Highly expressed in small intestine and adipose tissue and present at lower levels in testis, heart, pancreas, colon and skeletal muscle, Intelectin-1 exists as a disulfide-linked homotrimer that functions to enhance Insulin-stimulated glucose uptake and is also thought to participate in host defense against miccroorganisms. In addition to its roles in glucose regulation and immune system function, Intelectin-1 may also be involved in iron metabolism and obesity regulation in adults. Intelectin-2 shares 85% amino acid identity with Intelectin-1 and, like Intelectin-1, is a secreted protein that contains one fibrinogen C-terminal domain and is thought to play a role in the host defense system. While Intelectin-1 is present in a variety of tissues, Intelectin-2 exists only in the small intestine.
Synonyms	Endothelial lectin HL-1; Galactofuranose-binding lectin; Intelectin-1; Intestinal lactoferrin receptor; ITLN-1; Omentin
Note	For research use only, not for use in diagnostic procedure.
Reference Data

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