ITLN1 Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	WB
Recommend Dilution	WB: 1:2000~1:5000 IHC: 1:50~1:200
Reactivity	Pig, Human
Host	Rabbit
Clonality	Polyclonal
Immunogen	Synthetic peptide, corresponding to Human LFR.
Specificity	LFR polyclonal antibody detects endogenous levels of LFR protein.
Isotype	IgG
Formulation	Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.4.
Concentration	1mg/ml
Conjugation	Unconjugated
Storage Condition	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Predicted Protein Size	~ 35 kDa
Gene Name	intelectin 1
Database Link	Entrez Gene 55600 Human UniProt ID Q8WWA0
Background	Intelectin-1, also known as ITLN1, INTL, Omentin or LFR, is a 313 amino acidprotein that contains one fibrinogen C-terminal domain and is either secretedor lipid-anchored to the cell membrane. Highly expressed in small intestineand adipose tissue and present at lower levels in testis, heart, pancreas, colonand skeletal muscle, Intelectin-1 exists as a disulfide-linked homotrimer thatfunctions to enhance Insulin-stimulated glucose uptake and is also thought toparticipate in host defense against miccroorganisms. In addition to its rolesin glucose regulation and immune system function, Intelectin-1 may also beinvolved in iron metabolism and obesity regulation in adults. Intelectin-2shares 85% amino acid identity with Intelectin-1 and, like Intelectin-1, is asecreted protein that contains one fibrinogen C-terminal domain and is thoughtto play a role in the host defense system. While Intelectin-1 is present in avariety of tissues, Intelectin-2 exists only in the small intestine.
Synonyms	Endothelial lectin HL-1; Galactofuranose-binding lectin; Intelectin-1; Intestinal lactoferrin receptor; INTL; ITL; ITLN-1; LFR; Omentin; UNQ640/PRO1270
Note	For research use only, not for use in diagnostic procedure.
Reference Data

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